SP1 and IL1B

  • Number of citations of the paper that reports this interaction (PubMedID 22455954)
  • 9
  • Data Source:
  • BioGRID (two hybrid)

SP1

IL1B

Description Sp1 transcription factor interleukin 1 beta
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hypospadias (moderate to severe) ( 31856834)
  • Mean corpuscular hemoglobin ( 29403010)
  • Mean corpuscular volume ( 29403010)
  • Neutrophil percentage of white cells ( 27863252)
  • Parkinsonism in frontotemporal lobe dementia ( 29724592)
  • Percentage gas trapping ( 26030696)
  • Progressive supranuclear palsy ( 30089514)
  • Red blood cell count ( 27863252)
  • Reticulocyte count ( 27863252)
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Birth weight ( 31043758)
  • Dysmenorrheic pain severity ( 29855537)
  • Gestational age at birth (child effect) ( 31477735)
  • Post-term birth ( 31477735)
Interacting Genes 145 interacting genes: AATF AHR AKT1 AR ARHGAP21 ARNT ATF7IP ATF7IP2 BCL11B BCL6 BCOR BRCA1 CASP3 CASP6 CASP7 CBX5 CCNA1 CCNA2 CCND1 CD2 CDK1 CDK2 CEBPB CSNK2A1 CTCFL CTNNB1 DDX5 DROSHA E2F1 E2F2 E2F3 EGR1 ELF1 EP300 ESR1 ESR2 ESRRA ESRRB ESRRG ETS1 GABPA GATA1 GATA3 GATA4 HBZ HCFC1 HDAC1 HDAC2 HIF1A HINT1 HLTF HMGA1 HNF4A HOXC11 HSPA8 HTT IL1B JUN KIF1A KLF10 KLF4 KLF6 LDB1 LMO2 MAPK1 MAPK3 MAPK8 MBD1 MEF2C MEF2D MIER1 MIS18BP1 MSX1 MTREX MYC MYCN MYOD1 MYOG NAP1L1 NCOR1 NCOR2 NEPRO NFKB1 NFKB2 NFYA NFYB NFYC NKX3-1 NOS3 NPM1 NR2F1 NR5A1 NUP62 OGT PARP1 PER3 PML POGZ POU2F1 PPIG PPP1R13L PRKCZ PRKDC PSIP1 PSMC5 PURA RARA RB1 RBBP4 RBL1 REL RELA RNF4 RORA RXRA SENP6 SF3A1 SHC1 SMAD2 SMAD3 SMAD4 SMARCC1 SMARCC2 SOX10 SOX8 SP3 SP4 SREBF1 SREBF2 SRF SUB1 TAF4 TAL1 TBP TLX3 TP53 TP73 TPI1 USP39 VEGFA VHL YY1 ZBTB16 ZBTB2 ZBTB7A 15 interacting genes: A2M ADRB2 APP CASP1 CASP4 CMA1 EGR1 FYN IL1R1 IL1R2 IL1RAP LYN MMP2 PRTN3 SP1
Entrez ID 6667 3553
HPRD ID 01796 00985
Ensembl ID ENSG00000185591 ENSG00000125538
Uniprot IDs P08047 P01584
PDB IDs 1SP1 1SP2 1VA1 1VA2 1VA3 1HIB 1I1B 1IOB 1ITB 1L2H 1S0L 1T4Q 1TOO 1TP0 1TWE 1TWM 21BI 2I1B 2KH2 2NVH 31BI 3LTQ 3O4O 3POK 41BI 4DEP 4G6J 4G6M 4GAF 4GAI 4I1B 5BVP 5I1B 5MVZ 6I1B 7I1B 9ILB
Enriched GO Terms of Interacting Partners?
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