SP4 and ATXN7L1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SP4	ATXN7L1
Description		Sp4 transcription factor	ataxin 7 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 29348612) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Bipolar disorder ( 31043756) General cognitive ability ( 29844566) Major depressive disorder ( 20125088) Major depressive disorder (broad) ( 20038947) Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma) ( 23103227) Multisite chronic pain ( 31194737) Schizophrenia ( 30285260) Temporomandibular joint disorder ( 28081371)	Alzheimer's disease (late onset) ( 22881374) Blond vs. brown/black hair color ( 30531825) Dental caries ( 23064961) Heel bone mineral density ( 30598549 28869591) Obesity-related traits ( 23251661) Smoking cessation in chronic obstructive pulmonary disease ( 29631575)
Interacting Genes		16 interacting genes: - ADAM15 ATXN7L1 BANP CIB3 COL8A1 E2F1 FOXP2 LMO3 NKX3-1 NRF1 POU2F1 PRR20A SERF2 SP1 ZBTB7A	5 interacting genes: KRT31 KRTAP10-9 PHF1 SP4 SSPOP
Entrez ID		6671	222255
HPRD ID		02764	12508
Ensembl ID		ENSG00000105866	ENSG00000146776
Uniprot IDs		A0A3B3IRW4 Q02446 Q32M51	A4D0Q3 Q9BTQ8 Q9ULK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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