ATXN7L1 and PHF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ATXN7L1	PHF1
Description		ataxin 7 like 1	PHD finger protein 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Centrosome ESC/E(Z) Complex Site Of Double-strand Break
	Molecular Function	Protein Binding	DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process		Chromatin Organization Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation
Pathways			PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 22881374) Blond vs. brown/black hair color ( 30531825) Dental caries ( 23064961) Heel bone mineral density ( 30598549 28869591) Obesity-related traits ( 23251661) Smoking cessation in chronic obstructive pulmonary disease ( 29631575)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
Interacting Genes		5 interacting genes: KRT31 KRTAP10-9 PHF1 SP4 SSPOP	24 interacting genes: ATXN7L1 BIRC7 BRD2 CALCOCO2 EZH2 H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C6 H3C7 H3C8 H4C1 HSD17B14 NAB2 NEK6 PDLIM7 RBPMS TFCP2 THAP1 TRIM23 VAC14
Entrez ID		222255	5252
HPRD ID		12508	04195
Ensembl ID		ENSG00000146776	ENSG00000112511
Uniprot IDs		A4D0Q3 Q9BTQ8 Q9ULK2	A0A140VJR4 A0A1U9X8A3 O43189
PDB IDs			2E5P 2M0O 4HCZ 5XFN 5XFO 5XFP
Enriched GO Terms of Interacting Partners?
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