SNRPC and MAGED1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SNRPC	MAGED1
Description		small nuclear ribonucleoprotein polypeptide C	MAGE family member D1
Image			No pdb structure
GO Annotations	Cellular Component	Commitment Complex Nucleoplasm U1 SnRNP Cajal Body U2-type Prespliceosome	Chromatin Nucleus Cytoplasm Plasma Membrane Protein-containing Complex
	Molecular Function	RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Zinc Ion Binding U1 SnRNA Binding Pre-mRNA 5'-splice Site Binding Protein Homodimerization Activity U1 SnRNP Binding	Transcription Coactivator Activity Protein Binding Identical Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Positive Regulation Of MAP Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of Apoptotic Signaling Pathway
Pathways		mRNA Splicing - Major Pathway	NRAGE signals death through JNK Caspase activation via Dependence Receptors in the absence of ligand
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) HDL cholesterol ( 25961943) Obese vs. thin ( 30677029) Systemic lupus erythematosus ( 24871463)
Interacting Genes		28 interacting genes: AGGF1 DDX42 EWSR1 EXOSC8 FAM168A GOLGA2 HNRNPD HNRNPF HNRNPH2 HNRNPUL1 HSD17B14 ILF3 KHDRBS3 MAGED1 NCAPH2 PSMA3 RBFOX2 RBM11 RBM4 RBPMS RFX6 RNF31 SNRNP70 SPAG8 SS18L1 TLE5 WDR77 WWP2	62 interacting genes: AKAP9 ARNT2 BAG3 BARD1 BHLHE40 BIRC8 BRCA2 C1orf94 CA8 CCDC33 DAB1 DAZAP2 DLX4 DLX5 EIF3J EIF4E2 EP300 GPR135 GRAP2 HGS HIVEP1 HNRNPLL KPNA2 KRTAP19-5 MAPK3 MDFI MEOX2 MPC1 MSX2 NGFR NOTCH1 NPAS4 NUMBL PITX1 PJA1 PJA2 PLK1 PRKAB2 PSMF1 RBFOX1 RBFOX2 RBM23 RBPMS RFX1 RHOXF2 RNF6 RNF8 ROR2 SIM2 SIRT7 SMAP2 SNRPC TFG TRAF4 TRIM28 TTC23 TTC32 TUBA4A UNC5A XIAP ZNF488 ZNF688
Entrez ID		6631	9500
HPRD ID		04630	02202
Ensembl ID		ENSG00000124562	ENSG00000179222
Uniprot IDs		P09234 Q5TAL4	Q9Y5V3
PDB IDs		2VRD 3CW1 4PJO 6ELD 6QX9
Enriched GO Terms of Interacting Partners?
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