SNRPC and HSD17B14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SNRPC	HSD17B14
Description		small nuclear ribonucleoprotein polypeptide C	hydroxysteroid 17-beta dehydrogenase 14
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GO Annotations	Cellular Component	Commitment Complex Nucleoplasm U1 SnRNP Cajal Body U2-type Prespliceosome	Cytosol
	Molecular Function	RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Zinc Ion Binding U1 SnRNA Binding Pre-mRNA 5'-splice Site Binding Protein Homodimerization Activity U1 SnRNP Binding	Estradiol 17-beta-dehydrogenase Activity Protein Binding Identical Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity
	Biological Process	Spliceosomal SnRNP Assembly MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome	Estrogen Biosynthetic Process Steroid Catabolic Process Oxidation-reduction Process
Pathways		mRNA Splicing - Major Pathway	Estrogen biosynthesis
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) HDL cholesterol ( 25961943) Obese vs. thin ( 30677029) Systemic lupus erythematosus ( 24871463)	Blood protein levels ( 30072576) Resting metabolic rate ( 28476931)
Interacting Genes		28 interacting genes: AGGF1 DDX42 EWSR1 EXOSC8 FAM168A GOLGA2 HNRNPD HNRNPF HNRNPH2 HNRNPUL1 HSD17B14 ILF3 KHDRBS3 MAGED1 NCAPH2 PSMA3 RBFOX2 RBM11 RBM4 RBPMS RFX6 RNF31 SNRNP70 SPAG8 SS18L1 TLE5 WDR77 WWP2	16 interacting genes: CA8 CDKN2D CYTOR DDIT3 MIA3 MIR4435-2HG MPG NEK6 NTAQ1 NUDT18 PHF1 PSMA1 SNAPC3 SNRPC SREK1IP1 TBC1D22B
Entrez ID		6631	51171
HPRD ID		04630	16801
Ensembl ID		ENSG00000124562	ENSG00000087076
Uniprot IDs		P09234 Q5TAL4	A0A140VJH8 Q9BPX1
PDB IDs		2VRD 3CW1 4PJO 6ELD 6QX9	1YDE 5EN4 5HS6 5ICM 5ICS 5JS6 5JSF 5L7T 5L7W 5L7Y 5O42 5O43 5O6O 5O6X 5O6Z 5O72 5O7C 6EMM 6FFB 6G4L 6GBT 6GTB 6GTU 6H0M 6HNO
Enriched GO Terms of Interacting Partners?
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