Description |
synuclein alpha |
glycogen synthase kinase 3 beta |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Lithium
- 3-[3-(2,3-Dihydroxy-Propylamino)-Phenyl]-4-(5-Fluoro-1-Methyl-1h-Indol-3-Yl)-Pyrrole-2,5-Dione
- SB-409513
- N-(4-Methoxybenzyl)-N'-(5-Nitro-1,3-Thiazol-2-Yl)Urea
- Staurosporine
- Indirubin-3'-Monoxime
- (3e)-6'-Bromo-2,3'-Biindole-2',3(1h,1'h)-Dione 3-Oxime
- Alsterpaullone
- Phosphoaminophosphonic Acid-Adenylate Ester
- 2-(1,3-benzodioxol-5-yl)-5-[(3-fluoro-4-methoxybenzyl)sulfanyl]-1,3,4-oxadiazole
- 5-[1-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-1,3,4-oxadiazole-2(3H)-thione
- (7S)-2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one
- N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- 5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine
- 3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-one
- N-[(1S)-2-amino-1-phenylethyl]-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide
- 4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE
- ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE
- (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
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Diseases |
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GWAS |
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- HDL cholesterol ( 24097068)
- HDL cholesterol levels ( 28334899)
- Hippocampal volume in Alzheimer's disease dementia ( 29274321)
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Interacting Genes |
123 interacting genes:
A1BG
ACTA1
ADAP2
AKT1
AMBRA1
ANXA6
APLP1
APP
ARHGAP15
ARPP19
BAD
BAG5
BCL2L1
BDH2
CALM1
CAV1
CDC42EP2
CDC42EP3
CDC42SE1
CDK4
COL25A1
CRYAB
CSNK1A1
CSNK1D
CSNK2A1
CSNK2A2
CTNND1
CTSD
CYCS
DMTN
DNAJC5
DOCK7
DYRK1A
EEF1A1
EGFR
EIF3G
ELK1
ENC1
ENSA
FBXL5
FGR
FKBP4
FYN
GABARAPL1
GAPDH
GBA
GRK1
GRK2
GRK5
GRK6
GSK3B
H1-1
H1-2
HSD17B4
HSP90AA1
HSPA1A
HSPA8
HSPB1
HSPB2
HSPB6
HSPB8
IARS1
KIAA1191
KLC1
KLK6
LYN
MAP1B
MAPK1
MAPK8IP1
MAPT
MEF2D
MT-CO1
MT-CO3
NEDD4
NEDD4L
PAK3
PDE4DIP
PDIA2
PELP1
PFDN2
PLCB2
PLD1
PLK1
PLK2
PLK3
PRDX1
PREP
PRKCE
PRKN
PTK2B
RABAC1
RNF10
SAP30BP
SDF4
SEPTIN4
SIAH2
SLC6A3
SMURF2
SNCAIP
SNCB
SPTBN1
SQSTM1
SRC
SRI
STAMBP
SYK
SYN1
TGM1
TH
TOR1A
TPPP
TUBA1A
UBB
UBC
USP2
USP47
USP7
USP8
YOD1
YWHAB
YWHAE
YWHAH
ZRANB1
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223 interacting genes:
ACLY
ACSBG1
ACTL6B
ADAP1
ADIRF
AKAP11
AKT1
AKT2
AKT3
APC
APP
AR
ARRB1
ASRGL1
ATP5IF1
ATXN3
AURKA
AXIN1
AXIN2
BAG6
BCL2A1
BCL2L1
BCL3
BEX1
BHLHE41
BICD1
BICD2
BRIX1
BTRC
BZW2
CABYR
CAMSAP3
CCND1
CCNE1
CDH1
CDK5
CDX2
CEBPA
CEBPD
CEBPZ
CENPB
CHD3
CIITA
CLEC3B
CREB1
CREB3L3
CREM
CSAD
CSNK2B
CST6
CTNNB1
CTNND1
DBI
DCTN1
DCTN2
DCTN3
DDIT4
DEAF1
DEFA1
DELEC1
DHX34
DISC1
DNAJC13
DNM1L
DNMT1
DNMT3L
DPYSL2
DUSP9
DYNC1I1
E2F1
EEF1G
EFTUD2
EIF2B5
EIF4EBP1
ENTPD6
ERG28
EYA1
FAM193B
FAM83D
FBN3
FBXO7
FBXW11
FEN1
FIBP
FKBP14
FOXO1
FRAT1
FRAT2
FZD5
GBP2
GIPC1
GJB5
GNB2
GPR39
GYS1
HDAC4
HNRNPD
HSP90AA1
HSPA4
IGHM
IGSF21
IKBKG
ILK
IQCG
IRF1
JUN
KDM1A
KHSRP
KIAA1191
KIF5B
KLF2
KLF5
LMO4
LPCAT1
LRP6
LUC7L2
MAP1B
MAP3K1
MAP3K4
MAP4
MAPK1
MAPT
MARK2
MASP1
MCL1
MDM2
MED24
MICAL1
MID1IP1
MITF
MPP1
MTF2
MTOR
MUC1
MYC
MYOCD
NAT9
NBR1
NCOA3
NDRG1
NFE2L1
NFE2L2
NFE2L3
NFKB1
NIN
NOTCH1
NOTCH2
NRBP1
NSFL1C
OGA
OGT
PDE4D
PFKFB4
PHLPP1
PIAS1
PIM2
PMAIP1
PPARGC1A
PPP1R2
PRKACA
PRKCA
PRKCB
PRKCZ
PRKDC
PSEN1
PTK2
PTN
PTPN1
PXN
QARS1
RAI1
RBPJ
RCAN1
RELB
RICTOR
RPL36AL
RPLP1
RPS2
RPS6KA1
RSU1
RXRA
SAP30BP
SGK1
SGK3
SLA
SMAD3
SNAI1
SNCA
SNCAIP
SOX10
SOX9
SPTBN4
SREBF1
SYNE4
TAZ
TLE1
TMEM132A
TMEM44
TONSL
TP53
TPPP
TRAF6
TSC2
TUBA1A
UBE2D1
UBR1
UBR5
UBXN6
UFM1
UPF3A
VIM
VPS51
WSB1
XIAP
XPNPEP1
YBX1
YBX3
YWHAZ
ZFPM1
ZHX1
ZNF135
ZNF227
ZNF746
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Entrez ID |
6622 |
2932 |
HPRD ID |
01227 |
05418 |
Ensembl ID |
ENSG00000145335
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ENSG00000082701
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Uniprot IDs |
H6UYS5
P37840
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P49841
Q6FI27
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PDB IDs |
1XQ8
2JN5
2KKW
2M55
2N0A
2X6M
3Q25
3Q26
3Q27
3Q28
3Q29
4BXL
4R0U
4R0W
4RIK
4RIL
4ZNN
5CRW
6A6B
6CT7
6CU7
6CU8
6FLT
6H6B
6OSJ
6OSL
6OSM
6PEO
6PES
6RT0
6RTB
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1GNG
1H8F
1I09
1J1B
1J1C
1O6K
1O6L
1O9U
1PYX
1Q3D
1Q3W
1Q41
1Q4L
1Q5K
1R0E
1UV5
2JDO
2JDR
2JLD
2O5K
2OW3
2UW9
2X39
2XH5
3CQU
3CQW
3DU8
3E87
3E88
3E8D
3F7Z
3F88
3GB2
3I4B
3L1S
3M1S
3MV5
3OW4
3PUP
3Q3B
3QKK
3SAY
3SD0
3ZDI
3ZRK
3ZRL
3ZRM
4ACC
4ACD
4ACG
4ACH
4AFJ
4B7T
4DIT
4EKK
4IQ6
4J1R
4J71
4NM0
4NM3
4NM5
4NM7
4PTC
4PTE
4PTG
5F94
5F95
5HLN
5HLP
5K5N
5KPK
5KPL
5KPM
5OY4
5T31
6B8J
6BUU
6GJO
6GN1
6H0U
6HK3
6HK4
6HK7
6NPZ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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