SLC22A1 and CERS2

Number of citations of the paper that reports this interaction (PubMedID 11543633)
12

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SLC22A1	CERS2
Description		solute carrier family 22 member 1	ceramide synthase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Acetylcholine Transmembrane Transporter Activity Dopamine:sodium Symporter Activity Norepinephrine:sodium Symporter Activity Protein Binding Secondary Active Organic Cation Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity Identical Protein Binding	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity
	Biological Process	Neurotransmitter Transport Drug Transmembrane Transport Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Organic Cation Transport Quaternary Ammonium Group Transport Epinephrine Transport Norepinephrine Uptake Ammonium Transmembrane Transport Dopamine Uptake Acetate Ester Transport	Sphingolipid Biosynthetic Process Ceramide Biosynthetic Process Negative Regulation Of Axon Regeneration Negative Regulation Of Schwann Cell Migration Negative Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Pathways		Neurotransmitter clearance Norepinephrine Neurotransmitter Release Cycle Abacavir transmembrane transport Na+/Cl- dependent neurotransmitter transporters Organic cation transport	Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Gout ( 22179738) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Lipoprotein (a) levels ( 26377243) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolic traits ( 21886157) Prostate cancer ( 26034056 21743057) Serum metabolite levels ( 23093944) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995)	Body mass index ( 26426971) Estimated glomerular filtration rate ( 31152163 31015462) Facial attractiveness (female raters) ( 30946739) Glycated hemoglobin levels ( 28898252) HDL cholesterol ( 30275531) LDL cholesterol ( 24097068) LDL cholesterol levels ( 28334899) Reticulocyte fraction of red cells ( 27863252) Rhegmatogenous retinal detachment ( 23585552)
Interacting Genes		3 interacting genes: CERS2 OS9 POU2AF1	9 interacting genes: ASGR1 ASGR2 ATP6V0C HSP90AA1 PEX6 SLC19A2 SLC22A1 SLC39A1 TMBIM6
Entrez ID		6580	29956
HPRD ID		04007	06080
Ensembl ID		ENSG00000175003	ENSG00000143418
Uniprot IDs		O15245	Q96G23
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?