PLCG2 and LAT2

  • Number of citations of the paper that reports this interaction (PubMedID 12514734)
  • 47
  • Data Source:
  • HPRD (in vitro)

PLCG2

LAT2

Description phospholipase C gamma 2 linker for activation of T cells family member 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 28714976)
  • Blood protein levels ( 30072576)
  • Breast cancer (menopausal hormone therapy interaction) ( 24080446)
  • Coronary artery disease ( 29212778)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • Height ( 28552196)
  • Inflammatory bowel disease ( 28067908)
  • Mean platelet volume ( 27863252)
  • Metabolite levels ( 23823483)
  • Platelet distribution width ( 27863252)
  • Ulcerative colitis ( 28067908)
  • Upper eyelid morphology ( 29921221)
  • Venous thromboembolism ( 31420334 31676865)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Systemic lupus erythematosus ( 29848360)
Interacting Genes 50 interacting genes: ASB9 BLK BLNK BTK CBLB CD19 DAPP1 EGFR ELK1 EPOR EPYC ESD FCER1G FLT1 FYN GAB1 GAB2 GABPB2 HCK HSPD1 IRS1 ISL1 ITK JAK1 JAK2 KCTD17 KDR KHDRBS1 LAT LAT2 LCK LCP2 LHX8 LIME1 LYN NPM1 PRKD1 PTPN6 PTTG1 RALBP1 RTL10 SETD9 SH3BP2 SHC1 SYK TEC TP53 TWIST2 ZKSCAN7 ZNF512B 8 interacting genes: CBL EIF4H GAB1 GRB2 PLCG1 PLCG2 SOS1 UBQLN4
Entrez ID 5336 7462
HPRD ID 02570 09304
Ensembl ID ENSG00000197943 ENSG00000086730
Uniprot IDs P16885 Q9GZY6
PDB IDs 2K2J 2W2W 2W2X 3MAZ
Enriched GO Terms of Interacting Partners?
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