PLCG2 and DAPP1

  • Number of citations of the paper that reports this interaction (PubMedID 10770799)
  • 23
  • Data Source:
  • HPRD (in vivo, in vitro)

PLCG2

DAPP1

Description phospholipase C gamma 2 dual adaptor of phosphotyrosine and 3-phosphoinositides 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 28714976)
  • Blood protein levels ( 30072576)
  • Breast cancer (menopausal hormone therapy interaction) ( 24080446)
  • Coronary artery disease ( 29212778)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • Height ( 28552196)
  • Inflammatory bowel disease ( 28067908)
  • Mean platelet volume ( 27863252)
  • Metabolite levels ( 23823483)
  • Platelet distribution width ( 27863252)
  • Ulcerative colitis ( 28067908)
  • Upper eyelid morphology ( 29921221)
  • Venous thromboembolism ( 31420334 31676865)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 50 interacting genes: ASB9 BLK BLNK BTK CBLB CD19 DAPP1 EGFR ELK1 EPOR EPYC ESD FCER1G FLT1 FYN GAB1 GAB2 GABPB2 HCK HSPD1 IRS1 ISL1 ITK JAK1 JAK2 KCTD17 KDR KHDRBS1 LAT LAT2 LCK LCP2 LHX8 LIME1 LYN NPM1 PRKD1 PTPN6 PTTG1 RALBP1 RTL10 SETD9 SH3BP2 SHC1 SYK TEC TP53 TWIST2 ZKSCAN7 ZNF512B 21 interacting genes: BTK CNDP2 ERBB3 FCHSD2 GSTCD HSD3B7 HSPA1A LCK LYN MAP4K1 MGARP MYLIP PLAGL2 PLCG1 PLCG2 RBP7 RPL23 SRC TM4SF19 TNFAIP1 ZNHIT1
Entrez ID 5336 27071
HPRD ID 02570 05773
Ensembl ID ENSG00000197943 ENSG00000070190
Uniprot IDs P16885 J3KNB3 Q9UN19
PDB IDs 2K2J 2W2W 2W2X 1FAO 1FB8
Enriched GO Terms of Interacting Partners?
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