SGCD and FLNC

Number of citations of the paper that reports this interaction (PubMedID 10629222)
60

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SGCD	FLNC
Description		sarcoglycan delta	filamin C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Integral Component Of Membrane Sarcoplasmic Reticulum Sarcolemma	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere
	Molecular Function		Actin Binding Protein Binding Cytoskeletal Protein Binding Ankyrin Binding
	Biological Process	Muscle Organ Development Calcium-mediated Signaling Cellular Protein-containing Complex Localization Cardiac Muscle Tissue Development Cardiac Muscle Fiber Development Calcium Ion Homeostasis Heart Contraction Coronary Vasculature Morphogenesis Cardiac Muscle Cell Contraction	Cell Junction Assembly Muscle Fiber Development
Pathways			Cell-extracellular matrix interactions
Drugs
Diseases		Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD) Dilated cardiomyopathy (DCM)	Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS		Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Anthropometric traits ( 19260139) Daytime sleep phenotypes ( 27126917) Egg allergy ( 25710614) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Glycemic traits (pleiotropy) ( 31021400) HIV-1 viral setpoint ( 26039976) Multiple sclerosis (age of onset) ( 19010793) Obesity-related traits ( 23251661) Pulse pressure ( 30578418) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Resting-state electroencephalogram vigilance ( 29703947) Superior temporal sulcus banks volume ( 31530798)	Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		5 interacting genes: ADA FLNC SGCA SGCB SGCG	31 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2
Entrez ID		6444	2318
HPRD ID		03246	00018
Ensembl ID		ENSG00000170624	ENSG00000128591
Uniprot IDs		Q92629	Q14315 Q59H94
PDB IDs			1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX
Enriched GO Terms of Interacting Partners?
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