TRA2B and SRSF2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		TRA2B	SRSF2
Description		transformer 2 beta homolog	serine and arginine rich splicing factor 2
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GO Annotations	Cellular Component	Cell Nucleus Nuclear Inner Membrane Nucleoplasm Spliceosomal Complex Protein-containing Complex Perinuclear Region Of Cytoplasm Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol PML Body Nuclear Speck Interchromatin Granule
	Molecular Function	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Pre-mRNA Binding Identical Protein Binding	Transcription Corepressor Activity RNA Binding Protein Kinase C Binding Protein Binding Pre-mRNA Binding
	Biological Process	Response To Reactive Oxygen Species RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Cerebral Cortex Regionalization Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Cellular Response To Glucose Stimulus Embryonic Brain Development	Mitotic Cell Cycle Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Response To Vitamin E MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Height ( 31562340) Menarche (age at onset) ( 27182965 21102462 25231870) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		28 interacting genes: CDK6 CLK1 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM NGFR NXF1 RBMX RBMXL2 RBMY1A1 RNPS1 SREK1 SRPK1 SRPK2 SRSF10 SRSF2 SRSF3 SRSF4 SRSF6 SRSF9 TNPO3 USP13 YTHDC1 YWHAG YWHAZ ZRANB2	34 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRPK2 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2
Entrez ID		6434	6427
HPRD ID		04097	02888
Ensembl ID		ENSG00000136527	ENSG00000161547
Uniprot IDs		P62995	A0A024R8U5 Q01130 Q53FN0
PDB IDs		2CQC 2KXN 2RRA 2RRB	2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?
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