TRA2B and SRSF6

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (biochemical, two hybrid)

		TRA2B	SRSF6
Description		transformer 2 beta homolog	serine and arginine rich splicing factor 6
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Nuclear Inner Membrane Nucleoplasm Spliceosomal Complex Protein-containing Complex Perinuclear Region Of Cytoplasm Ribonucleoprotein Complex	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Pre-mRNA Binding Identical Protein Binding	RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process	Response To Reactive Oxygen Species RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Cerebral Cortex Regionalization Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Cellular Response To Glucose Stimulus Embryonic Brain Development	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Splice Site Selection RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Keratinocyte Proliferation MRNA 3'-end Processing Response To Insulin MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Negative Regulation Of Cell Death Regulation Of Wound Healing Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Height ( 31562340) Menarche (age at onset) ( 27182965 21102462 25231870) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)	Antibody level in response to infection ( 25758998) Daytime sleep phenotypes ( 27126917)
Interacting Genes		28 interacting genes: CDK6 CLK1 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM NGFR NXF1 RBMX RBMXL2 RBMY1A1 RNPS1 SREK1 SRPK1 SRPK2 SRSF10 SRSF2 SRSF3 SRSF4 SRSF6 SRSF9 TNPO3 USP13 YTHDC1 YWHAG YWHAZ ZRANB2	15 interacting genes: APP CLK1 LUC7L2 PPARGC1A RBM10 RNPS1 SF3B4 SREK1 SRPK1 SRPK2 SRSF4 TERF1 TERF2 TOE1 TRA2B
Entrez ID		6434	6431
HPRD ID		04097	09054
Ensembl ID		ENSG00000136527	ENSG00000124193
Uniprot IDs		P62995	Q13247
PDB IDs		2CQC 2KXN 2RRA 2RRB
Enriched GO Terms of Interacting Partners?
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