ADAP1 and SDCBP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ADAP1	SDCBP2
Description		ArfGAP with dual PH domains 1	syndecan binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle	Nucleolus Cytoplasm Plasma Membrane Nuclear Speck Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein C-terminus Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of GTPase Activity	Nervous System Development Cell Proliferation Intracellular Signal Transduction Intracellular Transport
Pathways		Nuclear signaling by ERBB4
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		23 interacting genes: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1	44 interacting genes: ADAP1 ARF4 BEND7 C1orf35 CT45A3 CT45A5 CTH DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 LGALS14 LGALS2 LYAR MED4 NFASC NKAPD1 NPM2 NRXN1 NUF2 PAFAH1B3 PRPF38A PRPF40A PRR13 PTMS RNPS1 RPL22 SDCBP SEC23A SREK1IP1 TDO2 THAP6 TIFA TM4SF1 TNP1 TRAF1 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		11033	27111
HPRD ID		09733	18032
Ensembl ID		ENSG00000105963	ENSG00000125775
Uniprot IDs		A8K3A2 B4DUZ7 O75689	Q9H190
PDB IDs		3FEH 3FM8 3LJU 3MDB
Enriched GO Terms of Interacting Partners?
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