CCBE1 and KLHL12

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCBE1	KLHL12
Description		collagen and calcium binding EGF domains 1	kelch like family member 12
Image		No pdb structure
GO Annotations	Cellular Component	Collagen Trimer Extracellular Space Extracellular Matrix	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle
	Molecular Function	Protease Binding Calcium Ion Binding Protein Binding Collagen Binding	Protein Binding Identical Protein Binding
	Biological Process	Lymphangiogenesis Sprouting Angiogenesis Respiratory System Process Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Protein Processing Lung Development Positive Regulation Of Angiogenesis Venous Blood Vessel Morphogenesis Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Lymphangiogenesis	Protein Monoubiquitination ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways			Degradation of DVL
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585) Major depressive disorder ( 23857890) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		6 interacting genes: CEP55 FBXO7 KLHL12 SIAH2 STX11 TOX4	46 interacting genes: ARAF ATXN1 BAG6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL2 DVL3 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL3 LNX1 MED28 MPP1 MRPL10 MTNR1A NDC80 NTAQ1 PDGFRB PEA15 PEF1 PRR13 RIT1 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TTBK2 UBE2I VEGFB VTA1 ZBP1
Entrez ID		147372	59349
HPRD ID		08703	13925
Ensembl ID		ENSG00000183287	ENSG00000117153
Uniprot IDs		Q6UXH8	Q53G59 Q9H7R2
PDB IDs			2VPJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?