RAP2A and FTL

Number of citations of the paper that reports this interaction (PubMedID 18624398)
14

Data Source:
BioGRID (two hybrid)

		RAP2A	FTL
Description		RAP2A, member of RAS oncogene family	ferritin light chain
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane	Extracellular Region Cell Cytoplasm Cytosol Intracellular Ferritin Complex Membrane Azurophil Granule Lumen Autolysosome Extracellular Exosome
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding	Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane	Iron Ion Transport Cellular Iron Ion Homeostasis Intracellular Sequestering Of Iron Ion Neutrophil Degranulation Iron Ion Homeostasis
Pathways			Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport
Drugs		Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate	Iron Dextran Protoporphyrin Sodium ferric gluconate complex
Diseases			Neurodegeneration with brain iron accumulation (NBIA); Hallervorden-Spatz syndrome; Neuroferritinopathy; Aceruloplasminemia
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)
Interacting Genes		31 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK	26 interacting genes: CLEC4G FTH1 GADD45A GLP1R GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MPHOSPH6 MPP6 MTNR1B MYOC MYOG PIK3CA PPP1CC PTN RAP2A SDCBP SMAD9 SPINK7 TAF10 USHBP1 VKORC1 ZDHHC17
Entrez ID		5911	2512
HPRD ID		01547	00616
Ensembl ID		ENSG00000125249	ENSG00000087086
Uniprot IDs		P10114	A0A384MDR3 P02792
PDB IDs		1KAO 2RAP 3RAP	2FFX 2FG4 2FG8 3KXU 4V6B 5LG8
Enriched GO Terms of Interacting Partners?
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