RAP1GDS1 and DOC2A

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		RAP1GDS1	DOC2A
Description		Rap1 GTPase-GDP dissociation stimulator 1	double C2 domain alpha
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GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Exosome	Nucleoplasm Nucleolus Lysosome Cell Junction Neuron Projection Extrinsic Component Of Synaptic Vesicle Membrane
	Molecular Function	GTPase Activator Activity Protein Binding	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	Vascular Smooth Muscle Contraction Myosin Filament Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of GTPase Activity Positive Regulation Of Mitochondrial Calcium Ion Concentration	Chemical Synaptic Transmission Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Spontaneous Neurotransmitter Secretion
Pathways
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Response to fenofibrate (total cholesterol levels) ( 27002377)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Height ( 28552196) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		19 interacting genes: ABCB7 ANTXR2 CDC42 DOC2A EGFR HRAS KIFAP3 KRAS LEF1 MBIP MED28 NRAS PLEKHB1 PTPRF PUF60 RAC1 RAP1A RHOA ZNF451	5 interacting genes: DYNLT1 RAP1GDS1 STXBP1 UBASH3B UNC13B
Entrez ID		5910	8448
HPRD ID		11763	05195
Ensembl ID		ENSG00000138698	ENSG00000149927
Uniprot IDs		B3KNU0 P52306 Q6U7G8	Q14183
PDB IDs		5XGC 5ZHX	4MJJ
Enriched GO Terms of Interacting Partners?
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