RAP1GDS1 and PLEKHB1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		RAP1GDS1	PLEKHB1
Description		Rap1 GTPase-GDP dissociation stimulator 1	pleckstrin homology domain containing B1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Exosome	Cytoplasm Integral Component Of Membrane
	Molecular Function	GTPase Activator Activity Protein Binding	Protein Binding
	Biological Process	Vascular Smooth Muscle Contraction Myosin Filament Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of GTPase Activity Positive Regulation Of Mitochondrial Calcium Ion Concentration	Multicellular Organism Development Phototransduction Regulation Of Cell Differentiation
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Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Response to fenofibrate (total cholesterol levels) ( 27002377)	Dimensional psychopathology (Cognitive) ( 29496196) Glucose homeostasis traits ( 25524916) Hand grip strength ( 27325353) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		19 interacting genes: ABCB7 ANTXR2 CDC42 DOC2A EGFR HRAS KIFAP3 KRAS LEF1 MBIP MED28 NRAS PLEKHB1 PTPRF PUF60 RAC1 RAP1A RHOA ZNF451	8 interacting genes: ACVR1 ATXN1 BMPR1B GNGT1 RAP1GDS1 SMAD1 TGFBR1 ZDHHC17
Entrez ID		5910	58473
HPRD ID		11763	09630
Ensembl ID		ENSG00000138698	ENSG00000021300
Uniprot IDs		B3KNU0 P52306 Q6U7G8	A0A024R5H7 A0A024R5H9 A0A024R5J2 Q9UF11
PDB IDs		5XGC 5ZHX
Enriched GO Terms of Interacting Partners?
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