DOC2A and UNC13B

Number of citations of the paper that reports this interaction (PubMedID 9195900)
44

Data Source:
HPRD (two hybrid, in vitro)

		DOC2A	UNC13B
Description		double C2 domain alpha	unc-13 homolog B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Lysosome Cell Junction Neuron Projection Extrinsic Component Of Synaptic Vesicle Membrane	Cell Golgi Apparatus Cytosol Plasma Membrane Membrane Cell Junction Synaptic Vesicle Membrane Neuromuscular Junction Early Phagosome Presynaptic Membrane Terminal Bouton Calyx Of Held Presynaptic Active Zone Ribbon Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse
	Molecular Function	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding	Calcium Ion Binding Protein Binding Calmodulin Binding Phospholipid Binding Syntaxin-1 Binding Rab GTPase Binding Diacylglycerol Binding GTP-dependent Protein Binding
	Biological Process	Chemical Synaptic Transmission Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Spontaneous Neurotransmitter Secretion	Chemical Synaptic Transmission Neurotransmitter Secretion Neuromuscular Junction Development Positive Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Maturation Negative Regulation Of Synaptic Plasticity Synaptic Transmission, Glutamatergic Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Protein Secretion Innervation Acrosomal Vesicle Exocytosis Dense Core Granule Priming Cellular Response To Glucose Stimulus Phagosome Maturation Positive Regulation Of Inhibitory Postsynaptic Potential Neuronal Dense Core Vesicle Exocytosis Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Defense Response To Bacterium
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Height ( 28552196) Schizophrenia ( 28991256 25056061 29483656)	Parkinson's disease ( 21812969)
Interacting Genes		5 interacting genes: DYNLT1 RAP1GDS1 STXBP1 UBASH3B UNC13B	10 interacting genes: CLK1 DOC2A DOC2B RIMS1 RPH3AL SPTBN2 STX1A STX1B STX2 TOE1
Entrez ID		8448	10497
HPRD ID		05195	05785
Ensembl ID		ENSG00000149927	ENSG00000198722
Uniprot IDs		Q14183	O14795 Q4LE73
PDB IDs		4MJJ
Enriched GO Terms of Interacting Partners?
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