RAP1GDS1 and MED28

		RAP1GDS1	MED28
Description		Rap1 GTPase-GDP dissociation stimulator 1	mediator complex subunit 28
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Exosome	Nucleoplasm Membrane Mediator Complex Cortical Actin Cytoskeleton
	Molecular Function	GTPase Activator Activity Protein Binding	Actin Binding Protein Binding
	Biological Process	Vascular Smooth Muscle Contraction Myosin Filament Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of GTPase Activity Positive Regulation Of Mitochondrial Calcium Ion Concentration	Stem Cell Population Maintenance Negative Regulation Of Smooth Muscle Cell Differentiation
Pathways			PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		19 interacting genes: ABCB7 ANTXR2 CDC42 DOC2A EGFR HRAS KIFAP3 KRAS LEF1 MBIP MED28 NRAS PLEKHB1 PTPRF PUF60 RAC1 RAP1A RHOA ZNF451	16 interacting genes: CBY2 FYN GRB2 GRPEL1 KLHL12 LCK MAGEA11 MED30 MED8 MED9 NF2 PRMT6 PUF60 RAP1GDS1 SRC USHBP1
Entrez ID		5910	80306
HPRD ID		11763	14381
Ensembl ID		ENSG00000138698	ENSG00000118579
Uniprot IDs		B3KNU0 P52306 Q6U7G8	Q9H204
PDB IDs		5XGC 5ZHX
Enriched GO Terms of Interacting Partners?
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