EIF5A2 and NIF3L1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EIF5A2	NIF3L1
Description		eukaryotic translation initiation factor 5A2	NGG1 interacting factor 3 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Pore Endoplasmic Reticulum Membrane Cytosol Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm Mitochondrion
	Molecular Function	Translation Elongation Factor Activity Protein Binding Ribosome Binding	Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	Translational Frameshifting Spermatogenesis Positive Regulation Of Cell Proliferation Polyamine Homeostasis Protein Transport Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination MRNA Transport	Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		Hypusine synthesis from eIF5A-lysine
Drugs
Diseases
GWAS		C-reactive protein levels ( 30388399) Urate levels ( 31578528)	Triptolide cytotoxicity ( 26121980)
Interacting Genes		8 interacting genes: CDC23 DHPS HIF1A NIF3L1 PTBP2 RAB30 REL SDCBP	67 interacting genes: AP5B1 APIP ARPIN BEND7 CCDC102B CCDC85B CDKN2B CDKN2C COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DUSP23 DYNLT3 EIF5A2 ENOX1 EPHB6 FXR2 GNMT GRB2 KCTD17 KRT15 KXD1 LAMTOR3 LMO2 MAGEA11 MAPRE2 MLXIPL NATD1 NME1 NOL3 NUDT14 NUDT21 ORC5 PAICS PCBD1 PNMA1 PRTFDC1 RABAC1 RAD54B RPIA S100A1 SAT1 SNF8 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SYT17 THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 VIM YES1 YWHAQ ZBED1
Entrez ID		56648	60491
HPRD ID		10426	10424
Ensembl ID		ENSG00000163577	ENSG00000196290
Uniprot IDs		Q9GZV4	A0A024R3V5 A0A024R3V7 Q9GZT8
PDB IDs
Enriched GO Terms of Interacting Partners?
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