ACTA1 and IQGAP1

  • Number of citations of the paper that reports this interaction (PubMedID 9199170)
  • 63
  • Data Source:
  • HPRD (in vitro)

ACTA1

IQGAP1

Description actin alpha 1, skeletal muscle IQ motif containing GTPase activating protein 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Allergic rhinitis ( 31361310)
  • Basophil percentage of granulocytes ( 27863252)
  • Basophil percentage of white cells ( 27863252)
  • Heel bone mineral density ( 30598549)
  • Lymphocyte counts ( 27863252)
  • Lymphocyte percentage of white cells ( 27863252)
  • Male-pattern baldness ( 28196072)
  • Multiple sclerosis ( 24076602)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 112 interacting genes: ABL1 ABRA ACTR10 ACTR1B ADSS2 AFAP1 AIF1 AJUBA AMOT ANXA2 BIN1 CCIN CCT2 CCT4 CCT5 CFL1 CLIC5 CNN1 CORO2B COTL1 CTNND1 CTTN CYFIP1 CYTH1 DHX9 DLG1 DMD DNASE1 DNMBP DTNA EGFR EPB41 EPB41L2 EPS8 FGD4 FHOD1 FSCN1 GAS2 GAS7 GC GSN HCLS1 HDAC4 HIP1R HSPB2 HTRA2 IQGAP1 ITGA2 ITPKA KIF23 KLHL20 LASP1 MACF1 MAP1A MAPT MIB2 MINPP1 MYL1 MYLK MYO10 MYO6 MYO7A MYO9B NEXN NR3C2 NRAP PAK1 PARVA PCYT1B PFDN1 PFN1 PHACTR1 PLD1 PPP1R9B PRKCA PRKCD PRKCE RAC1 RPS6KB1 S100A1 S100A4 SCIN SMTN SNCA SORBS1 SPRR1A SPTA1 SPTAN1 SPTBN2 TAGLN TJP1 TLN1 TMSB4X TMSB4Y TNNI1 TNNI3 TNNI3K TP53 TPM2 TPM3 TRIM55 TRIM63 TTN UBC USP25 USP6NL UTRN VASP VAV1 VCL VIL1 XIRP1 29 interacting genes: ACTA1 AIMP1 AKAP5 APC CALM1 CDC42 CDH1 CLIC5 CLIP1 CTNNB1 CYBB EGFR EZR GRIA4 KDR MAPK1 MEN1 MYL1 NPHS1 PDLIM7 PRKACA PTPRM RAC1 S100B STAU1 TSG101 UBE2I VASP YWHAQ
Entrez ID 58 8826
HPRD ID 00030 04541
Ensembl ID ENSG00000143632 ENSG00000140575
Uniprot IDs P68133 A0A024RC65 P46940
PDB IDs 1X0H 2RR8 3FAY 3I6X 5L0O
Enriched GO Terms of Interacting Partners?
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