STX6 and VPS11

Number of citations of the paper that reports this interaction (PubMedID 14623309)
7

Data Source:
HPRD (in vivo)

		STX6	VPS11
Description		syntaxin 6	VPS11 core subunit of CORVET and HOPS complexes
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Clathrin-coated Vesicle Integral Component Of Synaptic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Endocytic Vesicle HOPS Complex Late Endosome Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	Nucleotide Binding Protein Binding Protein Domain Specific Binding Syntaxin Binding Protein Binding, Bridging Metal Ion Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Endosome Organization Synaptic Vesicle To Endosome Fusion Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking Golgi Ribbon Formation Regulation Of Cellular Protein Localization	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Endosome To Lysosome Transport Regulation Of Protein Stability Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Regulation Of Organelle Assembly Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 30089514 21685912)	Body mass index ( 29273807) Coronary artery disease ( 29212778)
Interacting Genes		15 interacting genes: DNAJC5 EEA1 GOPC LMNA MARCHF2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX7 VAMP4 VPS11 VPS18	37 interacting genes: ALG9 BCAR1 BMI1 ECPAS EZR FUT1 GGA3 KDM1A KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MALL MARK3 MON1B MSN RAB7A RDX RILP RNF181 RNF26 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2D2 UBE2L3 UBE2U UVRAG VPS16 VPS18 VPS33A VPS45 WNT1
Entrez ID		10228	55823
HPRD ID		07231	12258
Ensembl ID		ENSG00000135823	ENSG00000160695
Uniprot IDs		O43752	A0A087WXL6 B7Z879 Q9H270
PDB IDs		2NPS 4J2C
Enriched GO Terms of Interacting Partners?
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