STX6 and DNAJC5

Number of citations of the paper that reports this interaction (PubMedID 29997244)
3

Data Source:
BioGRID (fluorescent resonance energy transfer)

		STX6	DNAJC5
Description		syntaxin 6	DnaJ heat shock protein family (Hsp40) member C5
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GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Clathrin-coated Vesicle Integral Component Of Synaptic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm	Mitochondrion Lysosomal Membrane Plasma Membrane Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	Protein Binding ATP-dependent Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Endosome Organization Synaptic Vesicle To Endosome Fusion Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking Golgi Ribbon Formation Regulation Of Cellular Protein Localization	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle
Pathways		Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Neutrophil degranulation GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS		Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 30089514 21685912)	Prostate cancer ( 23535732)
Interacting Genes		15 interacting genes: DNAJC5 EEA1 GOPC LMNA MARCHF2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX7 VAMP4 VPS11 VPS18	56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7
Entrez ID		10228	80331
HPRD ID		07231	08539
Ensembl ID		ENSG00000135823	ENSG00000101152
Uniprot IDs		O43752	Q6AHX3 Q9H3Z4
PDB IDs		2NPS 4J2C	2N04 2N05
Enriched GO Terms of Interacting Partners?
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