CCDC146 and NINL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC146	NINL
Description		coiled-coil domain containing 146	ninein like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole	Centrosome Cytosol Microtubule Intercellular Bridge
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process		G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring At Centrosome Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Body mass index ( 28892062) Response to amphetamines ( 22952603)	Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)
Interacting Genes		33 interacting genes: CBY2 CCDC136 CCNDBP1 CEP170P1 CEP44 DTNBP1 GOLGA2 KRT18 KRT19 KRT38 KRT40 MAGEA11 MAGEA6 MED4 MTUS2 NECAB2 NINL NUP62 PDE4DIP PNMA1 PSMC6 RINT1 RNF40 RPGRIP1 TFIP11 TNR TPM3 TRAF1 TRIM23 TRIM54 TSC22D4 USHBP1 VPS52	50 interacting genes: AKAP17A APEX2 APMAP AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 POLR3F RBM41 RCOR3 RGS2 RIBC2 SEC23B SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646
Entrez ID		57639	22981
HPRD ID		11150	11120
Ensembl ID		ENSG00000135205	ENSG00000101004
Uniprot IDs		Q8IYE0 Q96MS1	Q9Y2I6
PDB IDs
Enriched GO Terms of Interacting Partners?
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