NINL and FAM161A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NINL	FAM161A
Description		ninein like	FAM161 centrosomal protein A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Microtubule Intercellular Bridge	Astral Microtubule Photoreceptor Inner Segment Centrosome Spindle Microtubule Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Mitotic Spindle Mitotic Spindle Pole
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding Microtubule Binding Identical Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring At Centrosome Ciliary Basal Body-plasma Membrane Docking	Visual Perception Cilium Organization Response To Stimulus Cilium Assembly Positive Regulation Of Protein Acetylation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)	Atrial fibrillation ( 29892015) Erectile dysfunction ( 30583798) Systemic lupus erythematosus ( 28714469)
Interacting Genes		50 interacting genes: AKAP17A APEX2 APMAP AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 POLR3F RBM41 RCOR3 RGS2 RIBC2 SEC23B SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646	66 interacting genes: BEND3 BEND5 BRCA1 CADPS CALCOCO1 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC33 CCDC57 CCNDBP1 CDR2 CEP44 CEP57L1 CEP63 CEP70 DHX32 DOCK8 DVL2 EHMT2 FAM9B FSD2 GOLGA2 HMBOX1 IKZF1 KASH5 KIAA0753 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LMNA LZTS2 MCM6 MDFI MID2 MIPOL1 MTUS2 NECAB2 NINL NUTM1 PDE4DIP PHC2 PNMA2 PPFIA1 PPM1F RINT1 RUNDC3A SSX2IP STX11 SYCE1 TFIP11 TMCC2 TNIP1 TRAF1 TRIM15 TRIM37 TRIM54 TSGA10 TXLNB ZBTB1 ZBTB14 ZBTB43 ZBTB8A
Entrez ID		22981	84140
HPRD ID		11120	18996
Ensembl ID		ENSG00000101004	ENSG00000170264
Uniprot IDs		Q9Y2I6	Q3B820
PDB IDs
Enriched GO Terms of Interacting Partners?
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