NINL and TSPYL4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NINL	TSPYL4
Description		ninein like	TSPY like 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Microtubule Intercellular Bridge	Nucleus
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring At Centrosome Ciliary Basal Body-plasma Membrane Docking	Nucleosome Assembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)	Fast beta electroencephalogram ( 28040410) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Metabolite levels ( 23823483)
Interacting Genes		50 interacting genes: AKAP17A APEX2 APMAP AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 POLR3F RBM41 RCOR3 RGS2 RIBC2 SEC23B SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646	8 interacting genes: CCDC85B CDK5RAP3 CELSR3 NAP1L3 NINL PNMA1 TFIP11 TRIM38
Entrez ID		22981	23270
HPRD ID		11120	18236
Ensembl ID		ENSG00000101004	ENSG00000187189
Uniprot IDs		Q9Y2I6	Q9UJ04
PDB IDs
Enriched GO Terms of Interacting Partners?
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