PTH2R and HMG20A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PTH2R	HMG20A
Description		parathyroid hormone 2 receptor	high mobility group 20A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Nucleus
	Molecular Function	Parathyroid Hormone Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation
Pathways		Class B/2 (Secretin family receptors) G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Parathyroid hormone
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anthropometric traits ( 30576415) Metabolite levels ( 23823483) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744)	Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 30718926 28869590)
Interacting Genes		5 interacting genes: CALM1 GRHPR HMG20A PTH PTH2	25 interacting genes: ADD1 BRAP CCDC136 CCNK CFAP53 DCTN4 DTNA DTNB FBXO7 FMNL1 GTF2A1L HMG20B HPCAL1 KPNA2 MAGOHB PHF21A PSTPIP1 PTH2R RBM7 RPP30 RSPH9 SCNM1 SMAD4 SYTL4 TESC
Entrez ID		5746	10363
HPRD ID		03276	16116
Ensembl ID		ENSG00000144407	ENSG00000140382
Uniprot IDs		B4DFN8 P49190	B4DMG1 Q9NP66
PDB IDs
Enriched GO Terms of Interacting Partners?
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