PTH2R and GRHPR

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PTH2R	GRHPR
Description		parathyroid hormone 2 receptor	glyoxylate and hydroxypyruvate reductase
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Peroxisomal Matrix Cytosol Extracellular Exosome Catalytic Complex
	Molecular Function	Parathyroid Hormone Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding	Glycerate Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Hydroxypyruvate Reductase Activity Glyoxylate Reductase (NADP) Activity Carboxylic Acid Binding Protein Homodimerization Activity NAD Binding NADPH Binding
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis	Excretion Cellular Nitrogen Compound Metabolic Process Dicarboxylic Acid Metabolic Process Glyoxylate Metabolic Process Oxidation-reduction Process
Pathways		Class B/2 (Secretin family receptors) G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Glyoxylate metabolism and glycine degradation
Drugs		Parathyroid hormone
Diseases			Primary hyperoxaluria (HP)
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anthropometric traits ( 30576415) Metabolite levels ( 23823483) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744)	Bipolar disorder ( 31043756) Chronotype ( 30696823) Morning person ( 30696823) Severe bacterial meningitis ( 31092817)
Interacting Genes		5 interacting genes: CALM1 GRHPR HMG20A PTH PTH2	6 interacting genes: CDC7 FOS GLS2 LIG4 LSM1 PTH2R
Entrez ID		5746	9380
HPRD ID		03276	05052
Ensembl ID		ENSG00000144407	ENSG00000137106
Uniprot IDs		B4DFN8 P49190	A0A384N605 Q9UBQ7
PDB IDs			2GCG 2H1S 2Q50 2WWR
Enriched GO Terms of Interacting Partners?
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