THAP11 and THAP7

Number of citations of the paper that reports this interaction (PubMedID 18585351)
77

Data Source:
HPRD (in vitro)

		THAP11	THAP7
Description		THAP domain containing 11	THAP domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Cytosol Intercellular Bridge	Nuclear Chromatin Nucleoplasm Nuclear Speck Nuclear Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Metal Ion Binding Protein N-terminus Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Red blood cell count ( 27863252) Schizophrenia ( 25056061 29483656)
Interacting Genes		18 interacting genes: C9orf16 CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 HEMGN LRRC45 MCPH1 PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52	35 interacting genes: APP CCDC85B CCNDBP1 EHMT2 FBXO7 GNAI1 GOLGA2 H3C1 H4C1 HCFC1 HDAC3 KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 LNX1 LURAP1 LZTS2 MAP1LC3B MDFI MID2 MTUS2 NOTCH2NLA PELI2 PHC2 PIN1 PPP3CC SET TAF1B TFIP11 THAP11 TRAF1 TRAF2 ZDHHC17
Entrez ID		57215	80764
HPRD ID		11629	15500
Ensembl ID		ENSG00000168286	ENSG00000184436
Uniprot IDs		Q96EK4	Q9BT49
PDB IDs		2LAU 5AJS
Enriched GO Terms of Interacting Partners?
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