THAP11 and SLX1B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		THAP11	SLX1B
Description		THAP domain containing 11	SLX1 homolog B, structure-specific endonuclease subunit
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Cytosol Intercellular Bridge	Nucleoplasm Slx1-Slx4 Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding	Protein Binding Crossover Junction Endodeoxyribonuclease Activity 5'-flap Endonuclease Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Telomere Maintenance Via Telomere Lengthening Interstrand Cross-link Repair Telomeric D-loop Disassembly Nucleic Acid Phosphodiester Bond Hydrolysis T-circle Formation Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of T-circle Formation
Pathways			Resolution of D-loop Structures through Holliday Junction Intermediates Fanconi Anemia Pathway
Drugs
Diseases
GWAS		Red blood cell count ( 27863252) Schizophrenia ( 25056061 29483656)
Interacting Genes		18 interacting genes: C9orf16 CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 HEMGN LRRC45 MCPH1 PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52	4 interacting genes: DCTPP1 DUSP10 THAP11 TUBA1B
Entrez ID		57215	79008
HPRD ID		11629	14673
Ensembl ID		ENSG00000168286	ENSG00000181625
Uniprot IDs		Q96EK4	Q9BQ83
PDB IDs		2LAU 5AJS
Enriched GO Terms of Interacting Partners?
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