ANKRD50 and CLNK

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		ANKRD50	CLNK
Description		ankyrin repeat domain 50	cytokine dependent hematopoietic cell linker
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome	Cytoplasm Protein-containing Complex
	Molecular Function	Protein Binding	SH3/SH2 Adaptor Activity Protein Binding Protein-containing Complex Binding
	Biological Process	Protein Transport Retrograde Transport, Endosome To Plasma Membrane	Positive Regulation Of Natural Killer Cell Cytokine Production Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 26252872) Gastric cancer ( 31383772) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Metabolite levels ( 23823483) Small vessel stroke ( 29123153)	Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)
Interacting Genes		5 interacting genes: APP CLNK PEX5 SMURF1 ZDHHC17	30 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD JAKMIP1 LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX
Entrez ID		57182	116449
HPRD ID		13843	14720
Ensembl ID		ENSG00000151458	ENSG00000109684
Uniprot IDs		Q8TB46 Q9ULJ7	Q7Z7G1
PDB IDs
Enriched GO Terms of Interacting Partners?
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