SUCLA2 and CMTM5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		SUCLA2	CMTM5
Description		succinate-CoA ligase ADP-forming subunit beta	CKLF like MARVEL transmembrane domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Succinate-CoA Ligase Complex Extracellular Exosome	Extracellular Space Integral Component Of Membrane
	Molecular Function	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Protein Binding ATP Binding	Cytokine Activity Protein Binding
	Biological Process	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process Succinyl-CoA Pathway	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation
Pathways		Citric acid cycle (TCA cycle)
Drugs		Succinic acid
Diseases		Mitochondrial DNA depletion syndrome (MDS)
GWAS		Aging (time to event) ( 21782286) Colorectal cancer (diet interaction) ( 24743840) Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		6 interacting genes: AGTRAP ALAS2 ARL6IP1 CMTM5 FAM9B MTNR1A	54 interacting genes: AACS ACSF2 ALDH18A1 APOA1 ARMC9 COQ8A CPLX1 CREB3 CYP1A1 DDA1 ECPAS FAM114A1 FARS2 FERMT2 GAD1 GAD2 GLTP GOLGA2P10 GTF3C1 HNRNPK LMNA LMO2 MCEE MTERF3 MYG1 NDRG4 PIMREG PITPNC1 PLIN3 PNPO PPIF PPP2R3C PTPN9 RBFA RMDN2 RNF185 RSRC2 SDCBP SH3GLB1 SHMT2 SNX1 SPATA8 SPG21 SSX3 SUCLA2 SYNE4 TIMM44 TPD52L3 TTPA TUBB TUFM VARS2 ZNF391 ZNF599
Entrez ID		8803	116173
HPRD ID		06798	06986
Ensembl ID		ENSG00000136143	ENSG00000166091
Uniprot IDs		E5KS60 Q9P2R7 Q9Y4T0	Q96DZ9
PDB IDs		6G4Q
Enriched GO Terms of Interacting Partners?
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