BCCIP and ABCB1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		BCCIP	ABCB1
Description		BRCA2 and CDKN1A interacting protein	ATP binding cassette subfamily B member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Nucleoplasm Centrosome Centriole Cytosol Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole	Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Apical Plasma Membrane Extracellular Exosome External Side Of Apical Plasma Membrane
	Molecular Function	RNA Binding Protein Binding Tubulin Binding Kinase Regulator Activity	Transporter Activity Protein Binding ATP Binding Xenobiotic Transmembrane Transporting ATPase Activity Efflux Transmembrane Transporter Activity ATPase Activity Ubiquitin Protein Ligase Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances Xenobiotic Transmembrane Transporter Activity Phosphatidylcholine-translocating ATPase Activity Phosphatidylethanolamine-translocating ATPase Activity Ceramide-translocating ATPase Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization DNA Repair Cellular Response To DNA Damage Stimulus Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly	G2/M Transition Of Mitotic Cell Cycle Response To Drug Phospholipid Translocation Regulation Of Response To Osmotic Stress Transmembrane Transport Transepithelial Transport Stem Cell Proliferation Ceramide Translocation Export Across Plasma Membrane Positive Regulation Of Anion Channel Activity Drug Transport Across Blood-brain Barrier Regulation Of Chloride Transport
Pathways			Abacavir transmembrane transport ABC-family proteins mediated transport
Drugs			ATP Roxithromycin Voacamine Elacridar Tesmilifene FM-VP4 Miltefosine
Diseases
GWAS			Bone mineral density (spine) and age at menarche ( 26312577) Gallbladder cancer ( 28274756) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		17 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDKN1A CSNK2B H2BC15 ITSN2 PTN PTPRM RAD51 RPL23 SRC TENT5A TP53 YY1	11 interacting genes: BCCIP CAV1 CD4 HAX1 LNX1 MAPKAP1 MAPRE1 NEDD4 PIM1 PSMB8 RNF2
Entrez ID		56647	5243
HPRD ID		16542	01370
Ensembl ID		ENSG00000107949	ENSG00000085563
Uniprot IDs		Q9P287	A4D1D2 P08183
PDB IDs			6C0V 6FN1 6FN4 6QEX
Enriched GO Terms of Interacting Partners?
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