MAP3K4 and CHUK

  • Number of citations of the paper that reports this interaction (PubMedID 22547678)
  • 19
  • Data Source:
  • BioGRID (enzymatic study)

MAP3K4

CHUK

Description mitogen-activated protein kinase kinase kinase 4 component of inhibitor of nuclear factor kappa B kinase complex
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Aging ( 22773346)
  • Blood protein levels ( 28240269)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Lipoprotein (a) levels ( 26377243)
  • Ovarian disease with few adhesions ( 28333195)
Interacting Genes 26 interacting genes: ANXA2 AXIN1 BUB1B CDC42 CHUK CNTRL DIXDC1 GADD45A GADD45B GADD45G GSK3B MAP2K1 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPK13 MFHAS1 PTK2B PTPN11 RAC1 RACGAP1 RUNX2 TPR TRAF4 YWHAZ 81 interacting genes: AKT1 AKT2 AMBRA1 ATR BCL10 BCL3 BTRC CASP8 CDC37 CHEK1 COPS5 CREBBP CSF2RA CSNK2A1 CTNNB1 CUEDC2 CUL1 DCUN1D5 E2F4 EIF2AK2 ELP1 ERBIN ESR1 FKBP5 FOXO3 H3-4 H3C14 HSP90AA1 HSP90AB1 HTT IFIT5 IKBKB IKBKE IKBKG IRS1 MAP3K1 MAP3K11 MAP3K14 MAP3K4 MAP3K7 MAP3K8 NCOA3 NCOR1 NCOR2 NFKB1 NFKB2 NFKBIA NFKBIB NLRP4 NOTCH3 NR2C2 PAX8 PEBP1 PIAS1 PRKCB PRKCI PRKCQ PRKDC PTPN11 RELA RICTOR RIPK2 RPL27 SRC SRPK1 SRPK2 STAP2 TANK TGFBR1 TNFAIP3 TNFRSF1A TP53 TRAF2 TRAF3IP2 TRAF4 TRIM27 TRPC4AP UBC UBE2E3 UBE2I UBE2N
Entrez ID 4216 1147
HPRD ID 03886 02811
Ensembl ID ENSG00000085511 ENSG00000213341
Uniprot IDs Q9P1M2 Q9Y6R4 O15111
PDB IDs 3BRT 5EBZ 5TQW 5TQX 5TQY
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?