MAPK9 and JUNB

Number of citations of the paper that reports this interaction (PubMedID 8654373)
300

Data Source:
BioGRID (pull down)

		MAPK9	JUNB
Description		mitogen-activated protein kinase 9	JunB proto-oncogene, AP-1 transcription factor subunit
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol	Chromatin Nuclear Chromatin Nucleoplasm Transcription Factor Complex Transcription Factor AP-1 Complex
	Molecular Function	JUN Kinase Activity MAP Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Transcription Factor Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding
	Biological Process	Protein Phosphorylation JNK Cascade JUN Phosphorylation Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Peptidyl-serine Phosphorylation Positive Regulation Of Protein Ubiquitination Cellular Response To Reactive Oxygen Species Intracellular Signal Transduction Fc-epsilon Receptor Signaling Pathway Regulation Of Circadian Rhythm Rhythmic Process Regulation Of DNA-binding Transcription Factor Activity Protein Localization To Tricellular Tight Junction Cellular Response To Cadmium Ion Positive Regulation Of Podosome Assembly Positive Regulation Of Transcription Factor Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Response To Radiation Response To Mechanical Stimulus Response To Organic Substance Cytokine-mediated Signaling Pathway Osteoclast Differentiation Response To Lipopolysaccharide Cellular Response To Hormone Stimulus Cellular Response To Stress Osteoblast Proliferation Response To Cytokine Regulation Of Cell Proliferation Response To Drug Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Decidualization Response To CAMP Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion
Pathways		Oxidative Stress Induced Senescence FCERI mediated MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Activation of the AP-1 family of transcription factors	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Interleukin-4 and Interleukin-13 signaling NGF-stimulated transcription
Drugs		N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		77 interacting genes: ACP5 AKT1 ARRB1 ARRB2 ATF2 ATF7 BCL2L1 BCL2L11 C1orf94 CASP3 CCDC33 CDC25B CDC25C CEP126 CEP44 CLU CTBP1 CTNNB1 CYHR1 DUSP16 DUSP19 DUSP4 EEF2K EFHC2 EGFR ELK1 ELK3 FBXO7 GRB2 H3-3A HDAC9 HSF1 IRS1 JDP2 JUN JUNB JUND L3MBTL3 LMAN2 LNX1 LNX2 MACF1 MAP2K4 MAP2K7 MAP3K1 MAP3K10 MAPK8IP1 MAPK8IP2 MAPK8IP3 MAPKAPK5 MAPKBP1 MAPT MEOX1 NCF1 NCSTN NFATC3 NFATC4 PRKD1 PSEN1 RB1 RPS6KB1 SF3B4 SH3BP5 SHMT1 SMAD2 SMAD3 SMCO3 SSU72 TEX11 TOB1 TP53 TRAF2 TUSC2 WDR62 XPNPEP1 XPO7 ZBTB25	37 interacting genes: APLP2 ATF4 BATF BATF2 BCL6 BDNF BRCA1 DDIT3 DNMT3L EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 ITCH JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG USP24 ZNF595 ZSWIM9
Entrez ID		5601	3726
HPRD ID		04206	01303
Ensembl ID		ENSG00000050748	ENSG00000171223
Uniprot IDs		D7R525 D7R526 P45984	P17275 Q5U079
PDB IDs		3E7O 3NPC
Enriched GO Terms of Interacting Partners?
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