JUNB and USP24

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		JUNB	USP24
Description		JunB proto-oncogene, AP-1 transcription factor subunit	ubiquitin specific peptidase 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nuclear Chromatin Nucleoplasm Transcription Factor Complex Transcription Factor AP-1 Complex	Nucleoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Thiol-dependent Ubiquitinyl Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Response To Radiation Response To Mechanical Stimulus Response To Organic Substance Cytokine-mediated Signaling Pathway Osteoclast Differentiation Response To Lipopolysaccharide Cellular Response To Hormone Stimulus Cellular Response To Stress Osteoblast Proliferation Response To Cytokine Regulation Of Cell Proliferation Response To Drug Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Decidualization Response To CAMP Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion	Ubiquitin-dependent Protein Catabolic Process Viral Process Protein Deubiquitination
Pathways		SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Interleukin-4 and Interleukin-13 signaling NGF-stimulated transcription	Ub-specific processing proteases
Drugs
Diseases
GWAS			Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Metabolite levels ( 22916037) Methadone dose in opioid dependence ( 28115739) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		37 interacting genes: APLP2 ATF4 BATF BATF2 BCL6 BDNF BRCA1 DDIT3 DNMT3L EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 ITCH JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG USP24 ZNF595 ZSWIM9	5 interacting genes: CSNK2A1 DDB2 JUNB TP53 UBC
Entrez ID		3726	23358
HPRD ID		01303	11664
Ensembl ID		ENSG00000171223	ENSG00000162402
Uniprot IDs		P17275 Q5U079	Q9UPU5
PDB IDs
Enriched GO Terms of Interacting Partners?
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