PRKG1 and CFTR

  • Number of citations of the paper that reports this interaction (PubMedID 1377674)
  • 74
  • Data Source:
  • HPRD (in vitro)

PRKG1

CFTR

Description protein kinase cGMP-dependent 1 CF transmembrane conductance regulator
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Alcohol misuse (trauma interaction) ( 28265120)
  • Asthma ( 21907864)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 28552196)
  • Chlamydia trachomatis seropositivity ( 29967566)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Coronary artery disease ( 29212778)
  • Gait rhythm ( 26219847)
  • Height ( 28552196 31562340)
  • Interferon alpha levels in systemic lupus erythematosus ( 25338677)
  • Logical memory (delayed recall) in normal cognition ( 29274321)
  • Loneliness (multivariate analysis) ( 27629369)
  • Mammographic density (non-dense area) ( 25342443)
  • Mitochondrial DNA copy number ( 30704525)
  • Obesity-related traits ( 23251661)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 30285260)
  • Triglyceride levels x loop diuretics use interaction ( 31806883)
  • Barrett's esophagus or Esophageal adenocarcinoma ( 27527254)
  • Glaucoma ( 30054594)
  • Gout ( 22179738)
  • Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
  • Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 35 interacting genes: ANXA7 AR CFTR CREB1 CRIP2 FAM124A FHOD1 GABRR1 GKAP1 GTF2I HDAC1 IRAG1 ITPR1 LASP1 LMO2 NPR1 PDE5A PLCB3 PPP1R12A PPP1R12B PPP1R17 PRKCA RAF1 RGS2 RYR1 SELL SEPTIN3 SF1 SPP1 TNNT1 TRIM39-RPP21 TRPC3 VASP WDR77 ZNF646 29 interacting genes: CANX CLCN3 DERL1 DNAJA1 DNAJC5 EZR GOPC HSP90AA1 MARCHF2 NHS PDZD3 PDZK1 PPP2R1B PRKAA1 PRKACA PRKAR2A PRKCA PRKCE PRKG1 RNF5 SLC4A7 SLC4A8 SLC9A3R1 SLC9A3R2 SLC9A6 SNAP23 STUB1 STX1A UBE2I
Entrez ID 5592 1080
HPRD ID 08910 03883
Ensembl ID ENSG00000185532 ENSG00000001626
Uniprot IDs Q13976 A0A024R730 P13569
PDB IDs 1ZXA 3NMD 3OCP 3OD0 3OGJ 4KU7 4KU8 4QX5 4QXK 4R4L 4R4M 4Z07 5J48 5JAX 5JD7 5L0N 6BDL 6BG2 6C0T 1NBD 1XMI 1XMJ 2BBO 2BBS 2BBT 2LOB 2PZE 2PZF 2PZG 3GD7 3ISW 4WZ6 5D2D 5D3E 5D3F 5TF7 5TF8 5TFA 5TFB 5TFC 5TFD 5TFF 5TFG 5TFI 5TFJ 5TGK 5UAK 6HEP 6MSM 6O1V 6O2P
Enriched GO Terms of Interacting Partners?
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