PRKG1 and RGS2

  • Number of citations of the paper that reports this interaction (PubMedID 14608379)
  • 108
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

PRKG1

RGS2

Description protein kinase cGMP-dependent 1 regulator of G protein signaling 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Alcohol misuse (trauma interaction) ( 28265120)
  • Asthma ( 21907864)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 28552196)
  • Chlamydia trachomatis seropositivity ( 29967566)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Coronary artery disease ( 29212778)
  • Gait rhythm ( 26219847)
  • Height ( 28552196 31562340)
  • Interferon alpha levels in systemic lupus erythematosus ( 25338677)
  • Logical memory (delayed recall) in normal cognition ( 29274321)
  • Loneliness (multivariate analysis) ( 27629369)
  • Mammographic density (non-dense area) ( 25342443)
  • Mitochondrial DNA copy number ( 30704525)
  • Obesity-related traits ( 23251661)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 30285260)
  • Triglyceride levels x loop diuretics use interaction ( 31806883)
  • Coronary artery calcification ( 23870195)
  • Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes 35 interacting genes: ANXA7 AR CFTR CREB1 CRIP2 FAM124A FHOD1 GABRR1 GKAP1 GTF2I HDAC1 IRAG1 ITPR1 LASP1 LMO2 NPR1 PDE5A PLCB3 PPP1R12A PPP1R12B PPP1R17 PRKCA RAF1 RGS2 RYR1 SELL SEPTIN3 SF1 SPP1 TNNT1 TRIM39-RPP21 TRPC3 VASP WDR77 ZNF646 61 interacting genes: ADCY5 ADRA1A ADRB2 ARFGAP1 BBS10 CALM1 CEP126 CHD3 CLTA COMT COPB1 COPB2 CRMP1 CTSB DDR1 DUSP21 DYNLL1 EGFR EIF3L FZD5 GDE1 GIT1 GNA15 GNAI3 GNAQ GNAS HAUS5 HSPA8 IER3IP1 KLK8 LIG1 LRFN1 MARCHF6 METTL18 MON1A MTUS2 NINL NIPSNAP1 PPP1R9B PRKCA PRKCB PRKCG PRKCSH PRKG1 PRKN RAB2A RABAC1 RAP1B REEP5 RIN3 SCN5A SUN2 TSPAN15 TUBB2B UBC VPS29 WDR74 XRCC6 ZBTB48 ZNF579 ZYX
Entrez ID 5592 5997
HPRD ID 08910 02917
Ensembl ID ENSG00000185532 ENSG00000116741
Uniprot IDs Q13976 A0A024R939 P41220
PDB IDs 1ZXA 3NMD 3OCP 3OD0 3OGJ 4KU7 4KU8 4QX5 4QXK 4R4L 4R4M 4Z07 5J48 5JAX 5JD7 5L0N 6BDL 6BG2 6C0T 2AF0 2V4Z 4EKC 4EKD
Enriched GO Terms of Interacting Partners?
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