LMO3 and SP4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LMO3	SP4
Description		LIM domain only 3	Sp4 transcription factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nuclear Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Metal Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Fat Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glucocorticoid Receptor Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Household income (MTAG) ( 31844048) Tourette syndrome ( 30818990) Worry too long after an embarrassing experience ( 29500382)	Acute lymphoblastic leukemia (childhood) ( 29348612) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Bipolar disorder ( 31043756) General cognitive ability ( 29844566) Major depressive disorder ( 20125088) Major depressive disorder (broad) ( 20038947) Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma) ( 23103227) Multisite chronic pain ( 31194737) Schizophrenia ( 30285260) Temporomandibular joint disorder ( 28081371)
Interacting Genes		37 interacting genes: AIMP2 BANP BEND7 CARF CBY2 CCDC33 CCDC85B CEP170P1 CEP57L1 DVL2 FAM131C FBLIM1 FOS GABPB1 GOLGA2 HNRNPC HNRNPM IKZF1 KCTD1 KXD1 LDB1 LDB2 MBIP MDFI NBPF22P NHLH2 NUTM1 PHC2 PNMA1 RALYL RFX6 RORA SAMD3 SP4 TAX1BP1 ZBTB43 ZBTB8A	16 interacting genes: - ADAM15 ATXN7L1 BANP CIB3 COL8A1 E2F1 FOXP2 LMO3 NKX3-1 NRF1 POU2F1 PRR20A SERF2 SP1 ZBTB7A
Entrez ID		55885	6671
HPRD ID		11832	02764
Ensembl ID		ENSG00000048540	ENSG00000105866
Uniprot IDs		A0A024RAT1 Q8TAP4 Q9NYC6	A0A3B3IRW4 Q02446 Q32M51
PDB IDs
Enriched GO Terms of Interacting Partners?
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