VPS11 and STX6

Number of citations of the paper that reports this interaction (PubMedID 14623309)
7

Data Source:
HPRD (in vivo)

		VPS11	STX6
Description		VPS11 core subunit of CORVET and HOPS complexes	syntaxin 6
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Endocytic Vesicle HOPS Complex Late Endosome Membrane	Golgi Membrane Nucleoplasm Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Clathrin-coated Vesicle Integral Component Of Synaptic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleotide Binding Protein Binding Protein Domain Specific Binding Syntaxin Binding Protein Binding, Bridging Metal Ion Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Endosome To Lysosome Transport Regulation Of Protein Stability Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Regulation Of Organelle Assembly Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Early Endosome To Late Endosome Transport	Intracellular Protein Transport Vesicle Fusion Endosome Organization Synaptic Vesicle To Endosome Fusion Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking Golgi Ribbon Formation Regulation Of Cellular Protein Localization
Pathways			Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Body mass index ( 29273807) Coronary artery disease ( 29212778)	Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 30089514 21685912)
Interacting Genes		37 interacting genes: ALG9 BCAR1 BMI1 ECPAS EZR FUT1 GGA3 KDM1A KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MALL MARK3 MON1B MSN RAB7A RDX RILP RNF181 RNF26 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2D2 UBE2L3 UBE2U UVRAG VPS16 VPS18 VPS33A VPS45 WNT1	15 interacting genes: DNAJC5 EEA1 GOPC LMNA MARCHF2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX7 VAMP4 VPS11 VPS18
Entrez ID		55823	10228
HPRD ID		12258	07231
Ensembl ID		ENSG00000160695	ENSG00000135823
Uniprot IDs		A0A087WXL6 B7Z879 Q9H270	O43752
PDB IDs			2NPS 4J2C
Enriched GO Terms of Interacting Partners?
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