CDK5RAP2 and ERG28

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CDK5RAP2	ERG28
Description		CDK5 regulatory subunit associated protein 2	ergosterol biosynthesis 28 homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Spindle Pole Cell Cytoplasm Golgi Apparatus Centrosome Cytosol Cytoskeleton Microtubule Gamma-tubulin Ring Complex Cell Junction Microtubule Plus-end Perinuclear Region Of Cytoplasm Extracellular Exosome Mitotic Spindle Pole	Integral Component Of Membrane Transport Vesicle
	Molecular Function	Protein Binding Calmodulin Binding Microtubule Binding Tubulin Binding Protein Kinase Binding Gamma-tubulin Binding Transcription Regulatory Region DNA Binding	Molecular_function Protein Binding, Bridging
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Microtubule Bundle Formation Chromosome Segregation Centrosome Cycle Centriole Replication Brain Development Regulation Of G2/M Transition Of Mitotic Cell Cycle Neurogenesis Microtubule Organizing Center Organization Positive Regulation Of Microtubule Polymerization Regulation Of Neuron Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Centriole Replication Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Ciliary Basal Body-plasma Membrane Docking	Biological_process
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Primary microcephaly (MCPH)
GWAS		Asthma ( 27611488) Height ( 28552196) Photic sneeze reflex ( 27182965) Response to statin therapy ( 20339536) Rheumatoid arthritis ( 24782177)
Interacting Genes		26 interacting genes: ABCA2 CDK5 CDK5R1 CRMP1 EEF1G ERG28 FBXO25 HAP1 KAT5 LUC7L2 MAGEH1 MAPRE1 MRRF NEFL PCBD1 PHF19 PTN RBM48 REPS2 SENP2 STARD9 STK36 TBC1D4 TRIM37 TSNAX ZPR1	66 interacting genes: ALDH2 ANXA1 ANXA7 AQP2 BAIAP2 BID BTBD2 CCDC106 CCL18 CDC42 CDK5RAP2 CELF3 CLN8 COX17 CRADD CREB1 CREB3 CSTF2 DYNLL1 FAS FCGR2B FXR1 GADD45A GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSPE1 HYLS1 KLHL20 LMNA LSM2 MAPK8IP2 MPHOSPH6 MRPL38 MRPS12 MTNR1B NAT9 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PEX2 PFN1 PHYHIP POLE2 POLR2C POLR3F PPP1R8 PQBP1 RAB27A RPS6KA6 S100A8 SAT1 SEPHS1 SERPINB9 SNRPB SNRPG SULT1E1 TFG TK1 TSC22D1 TTR ZFP64 ZNF24
Entrez ID		55755	11161
HPRD ID		09740	05201
Ensembl ID		ENSG00000136861	ENSG00000133935
Uniprot IDs		A0A0A0MRG9 B3KVI2 B9EG74 Q7Z3M0 Q96SN8	Q6FII3 Q86TW5 Q9UKR5
PDB IDs
Enriched GO Terms of Interacting Partners?
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