PARVA and FERMT2

Number of citations of the paper that reports this interaction (PubMedID 25086068)
20

Data Source:
BioGRID (pull down)

		PARVA	FERMT2
Description		parvin alpha	fermitin family member 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Z Disc Lamellipodium	Stress Fiber Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Cell Cortex Cell Surface Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Lamellipodium Membrane I Band
	Molecular Function	Actin Binding Protein Binding Cadherin Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Actin Filament Binding
	Biological Process	Sprouting Angiogenesis Outflow Tract Septum Morphogenesis Establishment Or Maintenance Of Cell Polarity Regulation Of Cell Shape Cell Projection Assembly Actin Cytoskeleton Reorganization Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Cilium Assembly Actin-mediated Cell Contraction Smooth Muscle Cell Chemotaxis	Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Regulation Of Cell Shape Wnt Signaling Pathway Integrin Activation Cell Junction Assembly Substrate Adhesion-dependent Cell Spreading Focal Adhesion Assembly Protein Localization To Membrane
Pathways		Localization of the PINCH-ILK-PARVIN complex to focal adhesions Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Depressive symptoms (SSRI exposure interaction) ( 25649181) Diisocyanate-induced asthma ( 25918132) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Lung adenocarcinoma ( 28604730) Mortality in heart failure ( 20400778)	Alzheimer's disease (late onset) ( 24162737) Diastolic blood pressure ( 27841878) Glaucoma (primary angle closure) ( 27064256) Intraocular pressure ( 29617998 29785010 31959993 30054594) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 30046033) Prostate cancer ( 23535732) Pulse pressure ( 27841878) Systolic blood pressure ( 28135244 27841878)
Interacting Genes		15 interacting genes: ACTA1 APP ERO1B FERMT1 FERMT2 FERMT3 HSPB2 ILK LIMS1 MAP2K1 MLH1 NFE2L1 PXN UBE3A UBQLN1	8 interacting genes: APP CMTM5 FBLIM1 ILK ITGB1 LIMS1 PARVA TRIM15
Entrez ID		55742	10979
HPRD ID		16283	06374
Ensembl ID		ENSG00000197702	ENSG00000073712
Uniprot IDs		Q9NVD7	A0A024R687 Q96AC1
PDB IDs		2K2R 2VZC 2VZD 2VZG 2VZI 3KMU 3KMW 3REP 6MIB	2LGX 2LKO 2MSU 4F7H 6U4N
Enriched GO Terms of Interacting Partners?
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