FERMT2 and FBLIM1

Number of citations of the paper that reports this interaction (PubMedID 12679033)
137

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		FERMT2	FBLIM1
Description		fermitin family member 2	filamin binding LIM protein 1
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GO Annotations	Cellular Component	Stress Fiber Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Cell Cortex Cell Surface Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Lamellipodium Membrane I Band	Fibrillar Center Stress Fiber Cytosol Focal Adhesion Cell Junction
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Actin Filament Binding	Protein Binding Filamin Binding Metal Ion Binding
	Biological Process	Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Regulation Of Cell Shape Wnt Signaling Pathway Integrin Activation Cell Junction Assembly Substrate Adhesion-dependent Cell Spreading Focal Adhesion Assembly Protein Localization To Membrane	Regulation Of Cell Shape Regulation Of Integrin Activation Cell Junction Assembly Cell-cell Adhesion
Pathways		Cell-extracellular matrix interactions	Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 24162737) Diastolic blood pressure ( 27841878) Glaucoma (primary angle closure) ( 27064256) Intraocular pressure ( 29617998 29785010 31959993 30054594) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 30046033) Prostate cancer ( 23535732) Pulse pressure ( 27841878) Systolic blood pressure ( 28135244 27841878)	Alcoholic chronic pancreatitis ( 28754779) Cardiac Troponin-T levels ( 23247143) Gut microbiota (bacterial taxa) ( 27723756) Heel bone mineral density ( 30598549)
Interacting Genes		8 interacting genes: APP CMTM5 FBLIM1 ILK ITGB1 LIMS1 PARVA TRIM15	7 interacting genes: CUTA FERMT2 FLNA FLNB H3C1 LMO3 TRIM15
Entrez ID		10979	54751
HPRD ID		06374	09669
Ensembl ID		ENSG00000073712	ENSG00000162458
Uniprot IDs		A0A024R687 Q96AC1	Q8WUP2
PDB IDs		2LGX 2LKO 2MSU 4F7H 6U4N	2K9U 2W0P 4P3W
Enriched GO Terms of Interacting Partners?
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