FERMT2 and TRIM15

Number of citations of the paper that reports this interaction (PubMedID 25450970)
15

Data Source:
BioGRID (protein complementation assay)

		FERMT2	TRIM15
Description		fermitin family member 2	tripartite motif containing 15
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Cell Cortex Cell Surface Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Lamellipodium Membrane I Band
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Actin Filament Binding	Protein Binding Zinc Ion Binding
	Biological Process	Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Regulation Of Cell Shape Wnt Signaling Pathway Integrin Activation Cell Junction Assembly Substrate Adhesion-dependent Cell Spreading Focal Adhesion Assembly Protein Localization To Membrane	Mesodermal Cell Fate Determination Positive Regulation Of Type I Interferon Production Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of RIG-I Signaling Pathway Negative Regulation Of Intracellular Transport Of Viral Material Negative Regulation Of Viral Release From Host Cell
Pathways		Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 24162737) Diastolic blood pressure ( 27841878) Glaucoma (primary angle closure) ( 27064256) Intraocular pressure ( 29617998 29785010 31959993 30054594) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 30046033) Prostate cancer ( 23535732) Pulse pressure ( 27841878) Systolic blood pressure ( 28135244 27841878)	Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Neurociticism ( 29500382) Neuroticism ( 29255261)
Interacting Genes		8 interacting genes: APP CMTM5 FBLIM1 ILK ITGB1 LIMS1 PARVA TRIM15	36 interacting genes: ACD ACTB AXIN1 CFL1 CORO1B CTTN EHMT1 FAM151B FAM161A FBLIM1 FERMT2 FERMT3 GAB1 GTF2E1 IRF5 KEAP1 MED7 MSN MYBL2 NEXN PFN1 PRNP PTK2 PXN RABGEF1 ROCK1 SHC1 SNW1 SYK TAF9B TINF2 TRIM8 UBE2U VASP VCL VIM
Entrez ID		10979	89870
HPRD ID		06374	15551
Ensembl ID		ENSG00000073712	ENSG00000204610
Uniprot IDs		A0A024R687 Q96AC1	Q5SRL0 Q9C019
PDB IDs		2LGX 2LKO 2MSU 4F7H 6U4N
Enriched GO Terms of Interacting Partners?
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