PARVA and FERMT3

Number of citations of the paper that reports this interaction (PubMedID 25086068)
20

Data Source:
BioGRID (pull down)

		PARVA	FERMT3
Description		parvin alpha	fermitin family member 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Z Disc Lamellipodium	Podosome Extracellular Region Membrane Cell Junction Platelet Alpha Granule Lumen Cell Projection Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Cadherin Binding	Integrin Binding
	Biological Process	Sprouting Angiogenesis Outflow Tract Septum Morphogenesis Establishment Or Maintenance Of Cell Polarity Regulation Of Cell Shape Cell Projection Assembly Actin Cytoskeleton Reorganization Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Cilium Assembly Actin-mediated Cell Contraction Smooth Muscle Cell Chemotaxis	Platelet Degranulation Leukocyte Cell-cell Adhesion Integrin-mediated Signaling Pathway Positive Regulation Of Cell Migration Integrin Activation Regulation Of Cell-cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Platelet Aggregation
Pathways		Localization of the PINCH-ILK-PARVIN complex to focal adhesions Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	Platelet degranulation
Drugs
Diseases			Leukocyte adhesion deficiency (LAD), including the following four diseases: Leukocyte adhesion deficiency (I); Leukocyte adhesion deficiency (II); Leukocyte adhesion deficiency (III); LAD with Rac2 deficiency
GWAS		Depressive symptoms (SSRI exposure interaction) ( 25649181) Diisocyanate-induced asthma ( 25918132) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Lung adenocarcinoma ( 28604730) Mortality in heart failure ( 20400778)	Attention deficit hyperactivity disorder ( 21784300) Crohn's disease ( 28067908) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401)
Interacting Genes		15 interacting genes: ACTA1 APP ERO1B FERMT1 FERMT2 FERMT3 HSPB2 ILK LIMS1 MAP2K1 MLH1 NFE2L1 PXN UBE3A UBQLN1	9 interacting genes: APP EXOSC10 ILK ITGB1 LIMS1 LSM8 PARVA TINF2 TRIM15
Entrez ID		55742	83706
HPRD ID		16283	07440
Ensembl ID		ENSG00000197702	ENSG00000149781
Uniprot IDs		Q9NVD7	Q86UX7
PDB IDs		2K2R 2VZC 2VZD 2VZG 2VZI 3KMU 3KMW 3REP 6MIB	2YS3
Enriched GO Terms of Interacting Partners?
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