NAGK and SF3B3

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		NAGK	SF3B3
Description		N-acetylglucosamine kinase	splicing factor 3b subunit 3
Image
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Nucleus Nucleoplasm U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity	Nucleic Acid Binding Protein Binding Protein-containing Complex Binding
	Biological Process	N-acetylglucosamine Metabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Negative Regulation Of Protein Catabolic Process
Pathways		Synthesis of UDP-N-acetyl-glucosamine	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs		N-Acetylglucosamine	Quercetin
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)	Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		32 interacting genes: ACTR10 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82	29 interacting genes: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 NUTF2 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SNRNP200 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579
Entrez ID		55577	23450
HPRD ID		08441	12027
Ensembl ID		ENSG00000124357	ENSG00000189091
Uniprot IDs		A0A384N6G7 C9JEV6 Q9UJ70	A8K6V3 Q15393
PDB IDs		2CH5 2CH6	5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9
Enriched GO Terms of Interacting Partners?
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