SF3B3 and OSGEP

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		SF3B3	OSGEP
Description		splicing factor 3b subunit 3	O-sialoglycoprotein endopeptidase
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Plasma Membrane Nuclear Speck
	Molecular Function	Nucleic Acid Binding Protein Binding Protein-containing Complex Binding	Protein Binding Metal Ion Binding N(6)-L-threonylcarbamoyladenine Synthase Activity
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Negative Regulation Of Protein Catabolic Process	TRNA Threonylcarbamoyladenosine Modification
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	tRNA modification in the nucleus and cytosol
Drugs		Quercetin
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321)	Food addiction ( 27106561)
Interacting Genes		29 interacting genes: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 NUTF2 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SNRNP200 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579	23 interacting genes: CIAPIN1 CRIP2 EMCN GP1BA HPS6 LENG1 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 REX1BD SF3B3 SHC1 SP110 SPRED1 TNS1 WDR82 WIZ ZNF579 ZNF775
Entrez ID		23450	55644
HPRD ID		12027	10133
Ensembl ID		ENSG00000189091	ENSG00000092094
Uniprot IDs		A8K6V3 Q15393	Q9NPF4
PDB IDs		5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9	6GWJ
Enriched GO Terms of Interacting Partners?
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