MCM10 and ZBTB43

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MCM10	ZBTB43
Description		minichromosome maintenance 10 replication initiation factor	zinc finger and BTB domain containing 43
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Replication Fork Protection Complex	Nuclear Chromatin
	Molecular Function	DNA Replication Origin Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding Enzyme Binding Identical Protein Binding Metal Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication DNA Replication Initiation Cellular Response To DNA Damage Stimulus Cell Proliferation	Regulation Of Transcription By RNA Polymerase II
Pathways		Activation of ATR in response to replication stress Activation of the pre-replicative complex
Drugs
Diseases
GWAS			BMI (adjusted for smoking behaviour) ( 28443625) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Eyebrow thickness ( 26926045)
Interacting Genes		35 interacting genes: APP CALCOCO2 CCDC85B CCND1 CCND3 CDC45 CDC5L CDC6 CDC7 CDK6 CDKN1A CDKN2A CEP70 CEP72 DAPK1 DPPA2 GOLGA2 HAUS1 HOOK2 IKBKG KRT15 MCM2 MCM3 MCM6 MCM7 NINL ORC2 ORC3 ORC4 RECQL4 TNIP1 TRIM37 YWHAE ZBTB43 ZBTB8A	19 interacting genes: AEN AP1M1 ARR3 ARRB1 BDP1 DIP2A ELOA2 FAM161A LMO1 LMO3 LMO4 LNX1 MCM10 MORF4L2 PSMD3 SYT6 TRAF2 ZBTB24 ZNF417
Entrez ID		55388	23099
HPRD ID		11297	08346
Ensembl ID		ENSG00000065328	ENSG00000169155
Uniprot IDs		Q7L590	O43298
PDB IDs			2CSH
Enriched GO Terms of Interacting Partners?
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