MRGBP and YEATS4

Number of citations of the paper that reports this interaction (PubMedID 12963728)
94

Data Source:
HPRD (in vitro)

		MRGBP	YEATS4
Description		MRG domain binding protein	YEATS domain containing 4
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GO Annotations	Cellular Component	Nucleoplasm NuA4 Histone Acetyltransferase Complex	Nucleoplasm Nuclear Matrix Nuclear Membrane NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding	DNA Binding DNA-binding Transcription Factor Activity Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Acetylation Regulation Of Growth	Mitotic Cell Cycle Cytoskeleton Organization Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HATs acetylate histones	HATs acetylate histones Activation of the TFAP2 (AP-2) family of transcription factors
Drugs
Diseases
GWAS			Complete remission in asthma ( 29786918) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Height ( 31562340 18391951) Metabolite levels ( 23823483) Response to antidepressants (symptom remission) ( 29160301) Response to diuretic therapy ( 18591461) Response to SSRI in MDD or conscientiouness ( 29559929)
Interacting Genes		21 interacting genes: ACTB ACTL6A BRD8 DAPK1 DMAP1 HSPB1 ING1 KRTAP10-7 LRRK2 MEAF6 MFHAS1 MORF4L1 MORF4L2 MSL1 NOTCH2NLA RUVBL1 SH3BP4 TRRAP TUBB VAV2 YEATS4	13 interacting genes: CEP162 FRMD4A H3C1 MLLT10 MRGBP MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B
Entrez ID		55257	8089
HPRD ID		16646	03666
Ensembl ID		ENSG00000101189	ENSG00000127337
Uniprot IDs		Q9NV56	F8W0J4 O95619
PDB IDs		2N1D	5VNA 5VNB 5XTZ 5Y8V
Enriched GO Terms of Interacting Partners?
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