MRGBP and RUVBL1

Number of citations of the paper that reports this interaction (PubMedID 12963728)
94

Data Source:
HPRD (in vitro)

		MRGBP	RUVBL1
Description		MRG domain binding protein	RuvB like AAA ATPase 1
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GO Annotations	Cellular Component	Nucleoplasm NuA4 Histone Acetyltransferase Complex	Swr1 Complex Nucleus Nucleoplasm Microtubule Organizing Center Cytosol Membrane Nuclear Matrix Ino80 Complex NuA4 Histone Acetyltransferase Complex Extracellular Exosome MLL1 Complex R2TP Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding	TFIID-class Transcription Factor Complex Binding DNA Helicase Activity Transcription Coactivator Activity Protein Binding ATP Binding ATPase Activity TBP-class Protein Binding 5'-3' DNA Helicase Activity ADP Binding Cadherin Binding ATPase Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Acetylation Regulation Of Growth	Box C/D SnoRNP Assembly DNA Repair DNA Recombination Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cell Cycle Spermatogenesis Histone Acetylation Protein Deubiquitination DNA Duplex Unwinding CENP-A Containing Nucleosome Assembly Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Cell Division Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Nucleic Acid-templated Transcription Beta-catenin-TCF Complex Assembly Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		HATs acetylate histones	Telomere Extension By Telomerase Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex HATs acetylate histones UCH proteinases Ub-specific processing proteases DNA Damage Recognition in GG-NER Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) Gestational age at birth (maternal effect) ( 28877031) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		21 interacting genes: ACTB ACTL6A BRD8 DAPK1 DMAP1 HSPB1 ING1 KRTAP10-7 LRRK2 MEAF6 MFHAS1 MORF4L1 MORF4L2 MSL1 NOTCH2NLA RUVBL1 SH3BP4 TRRAP TUBB VAV2 YEATS4	20 interacting genes: ACTL6A CEP126 CTNNB1 DKC1 FBL LZTR1 MRGBP MYC NEDD4 OFD1 PLG RUVBL2 STOM SUMO2 TAF9 TBP TERT TK1 YY1 ZNHIT2
Entrez ID		55257	8607
HPRD ID		16646	09143
Ensembl ID		ENSG00000101189	ENSG00000175792
Uniprot IDs		Q9NV56	A0A384MTR5 B3KRS7 E7ETR0 Q9Y265
PDB IDs		2N1D	2C9O 2XSZ 5OAF 6FO1 6HTS 6IGM 6QI8 6QI9
Enriched GO Terms of Interacting Partners?
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